Accelerate to Discover

Back to filter

Related topics

New technologies to uncover the molecular basis of disorders of sex development

BioNano Genomics

Jul 13, 2018

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...

δT cells and CD8+ T cells targeting of breast cancer cells

Etaluma

Jul 11, 2018

Cancer stem cells (CSCs) are a large cause of metastasis in breast cancer. They are also very resistent to any...

Incucyte system used for generating single-cell-derived cancer-associated fibroblast clones

Sartorius

Jul 9, 2018

Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help...

Real-time verification of clonality using IncuCyte system

Sartorius

Jun 28, 2018

Use whole-well, label-free imaging to automatically scan for clones and verify monoclonality. Integrated image...

Jul 17, 2018

First DLS paper: Sorghum genome assembled with nanopore sequencing and DLS

BJS Biotechnologies

Jun 26, 2018

The new paper describes a chromosome-scale de novo assembly of the repeat-rich Sorghum bicolor Tx430 genome built using...

Real-time study of platelet formation under sheer-flow with Lumascope

Etaluma

Jun 18, 2018

Platelet formation was observed with Lumascope microscope in a uniform-sheer-flow biorector. Videos of the formation...

Early fetal sex determination using micro-volume of maternal plasma

BJS Biotechnologies

Jun 16, 2018

 A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early...

Jul 17, 2018

3R Compliant drug development studies

Bruker Biospin

Jun 8, 2018

In preclinical imaging, magnetic resonance imaging (MRI) can be an attractive alternative to researchers who have...

Show all topics (10)

Optical radionuclide imaging strategies for preclinical studies

Apr 13, 2017

Preclinical imaging is a key step in a variety of scientific endeavors, including basic understanding of biological processes and pharmaceutical research and development. Two common classes of preclinical molecular imaging methods are (1) optical techniques, including fluorescence and bioluminescence, and (2) nuclear techniques, including PET, SPECT, as well as new optical imaging techniques discussed in this note. In many cases, the goal of preclinical molecular imaging is to look at the uptake, distribution, or interaction of a specific targeted molecule in vivo. These agents are typically referred to as probes or tracers in optical and nuclear imaging, respectively.
These agents are typically labeled or tagged with a distinguishing moiety in order to actively track them. However, fluorescent tags can be large relative to the target molecule of interest. On the other hand, radiolabeling typically has very little or no effect on the molecular shape, size, or function of a tagged molecule and many radionuclides can be directly incorporated into the native structure of the molecule of interest.

Read more

Scientific paper
Application

Get more info

Miroslav Vecheta

Support Specialist

Miroslav

Vecheta

+420 737 202 127

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

With Fluorescence, Luminescence, Radioisotopic and Radiographic Imaging, Xtreme provides the ultimate combination of sensitivity, speed and flexibility

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey