Accelerate to discover

Back to filter

Related topics

Cytek webinar - the new age of spectral flow cytometry

Cytek Biosciences

Sep 9, 2019

The Cytek Aurora flow cytometer has made more than twenty-four color flow cytometry panels possible with only three...

New study resolves helicase dynamics and interactions during DNA replication using C-Trap

LUMICKS

Aug 30, 2019

Researchers from Rockefeller University used a C-Trap optical tweezers – fluorescence microscopy system to observe the...

Low-dose maging in a new preclinical total-body PET/CT scanner

Bruker Biospin

Aug 28, 2019

Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing...

Novel methods to analyze platelet activation with the NovoCyte flow cytometer

Acea Biosciences

Aug 26, 2019

Platelets are of large importance in medicine both for their essential role in hemostasis and thrombosis, as well as...

Sep 16, 2019

Assessment of pro-arrhythmic effects using xCELLigence Cardio system and Pluricyte Cardiomyocytes

Acea Biosciences

Aug 21, 2019

The combination of Pluricyte Cardiomyocytes and the xCELLigence RTCA Cardio ECR system enables  detailed ...

Bruker announces acquisition of preclinical and molecular imaging research software provider PMOD

Bruker Biospin

Aug 19, 2019

The PMOD software is widely used for the analysis of positron emission tomography (PET) studies in neurology,...

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

Sage Science

Aug 16, 2019

The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for...

Sep 16, 2019

Fluxion Biosciences launches custom liquid biopsy NGS panel development

Fluxion Biosciences

Aug 14, 2019

Fluxion a leading developer of precision solutions for life science research and diagnostics, announced that can...

Show all topics (10)

Optical radionuclide imaging strategies for preclinical studies

Apr 13, 2017

Preclinical imaging is a key step in a variety of scientific endeavors, including basic understanding of biological processes and pharmaceutical research and development. Two common classes of preclinical molecular imaging methods are (1) optical techniques, including fluorescence and bioluminescence, and (2) nuclear techniques, including PET, SPECT, as well as new optical imaging techniques discussed in this note. In many cases, the goal of preclinical molecular imaging is to look at the uptake, distribution, or interaction of a specific targeted molecule in vivo. These agents are typically referred to as probes or tracers in optical and nuclear imaging, respectively.
These agents are typically labeled or tagged with a distinguishing moiety in order to actively track them. However, fluorescent tags can be large relative to the target molecule of interest. On the other hand, radiolabeling typically has very little or no effect on the molecular shape, size, or function of a tagged molecule and many radionuclides can be directly incorporated into the native structure of the molecule of interest.

Read more

Scientific paper
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey