Accelerate to discover

Back to filter

Related topics

Early immune response in mice immunized with inactivated vaccine against SARS-CoV-2

Cytek Biosciences

Nov 19, 2020

The development of a vaccine against COVID-19 is a hot topic for many research laboratories all over the world. Our aim...

Bruker announces software provider PMOD Technologies LLC

Bruker Biospin

Nov 13, 2020

PMOD Technologies aims to equip researchers with best-in-class software tools for biomedical imaging research in humans...

Microvascular injury in mild traumatic brain injury accelerates alzheimer-like pathogenesis in mice

RWD

Nov 9, 2020

Traumatic brain injury (TBI) is considered as the most robust environmental risk factor for Alzheimer’s disease (AD)....

Discover the new NovoCyte Penteon - when exceptional performance meets simplicity

Agilent technologies

Nov 6, 2020

The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte. You now have the flexibility to...

Nov 24, 2020

CS-FNX Hitachi Koki, discover the state-of-art ultracentrifuges series

Hitachi Koki

Nov 4, 2020

Hitachi Koki, as a world leading producer of centrifuges offers general purpose floor standing and table top...

Curiox webinar - how to retain more cells for Single Cell Sequencing and proteogenomics ?

Curiox

Oct 28, 2020

Do you think that centrifuging cells at 500 x g is not going to cause issues? Moreover, sample prep involving...

Live animal imaging - Humane animal research

Bruker Biospin

Oct 26, 2020

Drawing on over 50 years of expertise in the life and animal sciences, Bruker designs preclinical imaging systems that...

Nov 24, 2020

3D time lapse imaging and quantitative analysis of multilayered Endothelial cells migration

Yokogawa

Oct 22, 2020

Time lapse confocal imaging has been an essential method to investigate the 3D dynamic behaviors of cells in tissue...

Show all topics (10)

Optical radionuclide imaging strategies for preclinical studies

Apr 13, 2017

Preclinical imaging is a key step in a variety of scientific endeavors, including basic understanding of biological processes and pharmaceutical research and development. Two common classes of preclinical molecular imaging methods are (1) optical techniques, including fluorescence and bioluminescence, and (2) nuclear techniques, including PET, SPECT, as well as new optical imaging techniques discussed in this note. In many cases, the goal of preclinical molecular imaging is to look at the uptake, distribution, or interaction of a specific targeted molecule in vivo. These agents are typically referred to as probes or tracers in optical and nuclear imaging, respectively.
These agents are typically labeled or tagged with a distinguishing moiety in order to actively track them. However, fluorescent tags can be large relative to the target molecule of interest. On the other hand, radiolabeling typically has very little or no effect on the molecular shape, size, or function of a tagged molecule and many radionuclides can be directly incorporated into the native structure of the molecule of interest.

Read more

Scientific paper
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey