Accelerate to discover

Back to filter

Related topics

Deep-Learning, Label-Free, Quantitative Cell Segmentation with IncuCyte

Sartorius & Essen BioScience

Sep 24, 2021

Sartorius Unveils LIVECell, a Deep-Learning Dataset for Label-Free, Quantitative Cell Segmentation in Nature Methods.

Meet ACCELA at International Conference Analytical Cytometry 2021

Cytek Biosciences

Sep 23, 2021

Meet us at International Conference Analytical Cytometry 2021. ACCELA will be present as...

The roles of preclinical optical imaging in cancer research

Spectral Instruments Imaging

Sep 22, 2021

Watch the last Spectral Instrument Imaging webinar with Dr. Michael Henry who will shares key data sets from his work...

See What's Possible with the PippinHT

Sage Science

Sep 14, 2021

Programmable DNA size selection enables new discoveries by helping optimize the library detected by a sequencer. That’s...

Sep 28, 2021

Magnetic resonance elastography techniques and preclinical applications

Bruker Biospin

Sep 14, 2021

It has been known for centuries that tissue stiffness can change in the presence of disease, but quantifying such...

Ex Vivo dental imaging is directly translatable to the clinic

Bruker Biospin

Sep 14, 2021

Although patients are too large in size for preclinical microCT scanners, it still has a big significance in clinical...

IncuCyte live cell analysis system for 3D Organoids discovery

Sartorius & Essen BioScience

Sep 10, 2021

Live-Cell Analysis has revolutionized numerous studies, with a wide selection of applications namely 3D Tumour Spheroid...

Sep 28, 2021

Introducing WOLF G2 - Benchtop microfluidic cell sorter

NanoCellect

Aug 31, 2021

The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...

Show all topics (10)

Simultaneous non-invasive in vivo imaging of apoptosis and angiogenesis in a mouse model

Oct 20, 2016

Baseline angiogenesis and apoptotic activities were simultaneous evaluated before initiation of the treatment (D0) using the Bruker In-Vivo Xtreme imaging system, after i.p. administration of Angiosense680 EX and Annexin750 probes, respectively, according to the instructions of the supplier. After 3 days of treatment (D3), angiogenesis and apoptotic activities were similarly assessed; GLPG1790, Flavopiridol or Bevacizumab treatments were given 2hr prior to imaging.
All images were captured by a cooled CCD camera with the following parameters: f-stop 1.1, binning 2, 2 sec acquisition time for Angiosense680 EX and 5 sec acquisition time for Annexin750.
For anatomical co-registration, a reflectance image (0.1 second acquisition time, f-stop 2.8, binning 1) and an X-ray image (1.2 second acquisition time, f-stop 4, 45 KVP energy, 2 mm filter) were performed.
For precise co-registration, all images were taken with a 190 mm field of view (FOV). For each mouse and each probe, results were expressed as the difference between Net intensity at D3 and D0.

Read more

Scientific paper
Technical breakthrough
Application

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey