Accelerate to discover

Back to filter

Related topics

Discover the newly re-designed TissueGnostics portfolio

TissueGnostics

Sep 18, 2020

TissueGnostics is a solution provider for Precision Medicine and provides fully integrated cutting-edge tissue...

Using DNA repair and machine learning to improve cancer risk prediction

Luminex

Sep 7, 2020

Across the world, breast cancer continues to be the leading type of cancer in women, accounting for 25% of all cases....

Quantitative evaluation of pulmonary function with hyperpolarized xenon gas MR

Bruker Biospin

Aug 20, 2020

Hyperpolarized 129Xe MR has been proven to be a powerful tool to evaluate the pulmonary function and has been widely...

Get more out of your full spectrum panel with Cytek’s new reagent family

Cytek Biosciences

Aug 17, 2020

Cytek Biosciences has already redefined what is possible in flow cytometry. The new Cytek cFluor family of reagents...

Sep 21, 2020

Applications of Hyperpolarized 129Xe MRI for functional imaging of the lungs

Bruker Biospin

Aug 11, 2020

2015 marked the first ever translation of hyperpolarized gas MRI to diagnostic clinical practice. Research at the...

Detection of Rare Cells and Circulating Tumor Cells using NovoCyte flow cytometer

Acea Biosciences

Aug 11, 2020

Circulating tumor cells (CTC) are rare cells shed from a solid tumor or metastases that circulate through the...

Introducing Amnis AI Image Analysis software

Luminex

Aug 4, 2020

Amnis AI Image Analysis Software combines the power of high dimensional data reduction with artificial intelligence,...

Sep 21, 2020

Micro-CT: Fancy gadget or indispensable technology towards quantification of lung diseases?

Bruker Biospin

Jul 29, 2020

Technology allowing evaluation of live animals repeatedly is indispensable to gain better insight into the dynamics of...

Show all topics (10)

The evaluation of three digital PCR platforms for residual disease in chronic myeloid leukemia

Oct 11, 2016

Thursday, October 13, 2016, 5 pm CEST

Mary Alikian, Ph.D., Imperial Molecular Pathology laboratory and the Department of Haematology at Hammersmith Hospital, Imperial College London

The BCR-ABL1 fusion gene sequence is used to help diagnose and monitor treatment and recurrence for chronic myelogenous leukemia (CML). In fact, between 90-95% of diagnosed CML cases are BCR-ABL1-positive. While reverse transcription quantitative PCR (RT-qPCR) is the gold standard strategy for monitoring BCR-ABL1 transcripts, there can often be challenges with reproducibility due to the technology and workflow. Reverse-Transcription Digital PCR (RT-dPCR) is an adaptation of this method that could provide the robust and standardized workflow needed for patient stratification. In this webinar, Dr. Mary Alikian at Hammersmith Hospital, Imperial College London, discussed her team’s comparison of three different available dPCR platforms (ThermoFisher Scientific’s QuantStudio 3D System, Bio-Rad’s QX200 System and RainDance’s RainDrop System) and investigation of whether they could be applied to a clinical research setting to quantify BCR-ABL1 transcripts in CML patients. The team determined that only the RainDrop System was able to detect and quantitatively measure BCR-ABL1 transcripts in the <0.001% range at a level higher than the false positive rate in the control patient groups.

Register now

Technical breakthrough
Webinar

Related technologies: Digital PCR

Get more info

Regina Fillerová

Field application specialist

Regina

Fillerová

+420 731 127 718

Send Message

Brand profile

RainDance Technologies

RainDance company’s ultra-sensitive genomic tools enable research of novel non-invasive liquid biopsy applications that should result in more accurate, reliable, cost-effective, and early detection of cancer and other inherited and infectious diseases.

Related products

Capable of generating more than a billion reactions in a single day, the RainDrop system surpasses all existing technologies and establishes a new performance standard in sensitivity, quantitation and multiplexing.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey