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In this webinar, Dr. Mathieu D. Santin from ICM, Paris, France, will describe methods and results obtained for in and ex vivo imaging at ultra-high field in the context of neurodegenerative diseases (demyelinating diseases, Alzheimer disease, multiple sclerosis…). For the investigation of such diseases at UHF Santin primarily implements Multi Gradient Echo (MGE) and 3D-segmented Diffusion EPI techniques. Other innovative studies combining ultrasound and MRI to open the blood brain barrier will be discussed as well. Focused Ultrasound (FUS) are used for instance for cortical activations in primates (Transcranial Focused Ultrasound) but also for non-invasively modulating the visual cortex activity of primates by local ultrasound-induced delivery of an inhibitory neurotransmitter (GABA) : transient disruption of the blood brain barrier (BBB) with FUS coupled with ultrasound contrast agents (UCA).
Presenter: Dr. Mathieu D. Santin, ICM, Paris, France
Related technologies: Magnetic resonance imaging
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Brand profile
Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
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www.bruker.com
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