Prostate cancer remains among the leading causes of cancer-related deaths in men. Loss of NOTCH1 in aggressive prostate cancer cells decreases proliferation, invasion, and tumorsphere formation.

MicroPET-based dosimetry of 152Tb is feasible, and the comparison with organ harvesting resulted in acceptable dose discrepancies for body districts that can be segmented on CT. 

Lower-grade gliomas are often characterized by mutations in metabolism-related genes isocitrate dehydrogenase 1 (IDH1) and IDH2. Resection of these tumors is constrained by adjacent eloquent cortex, resulting in local failures. 

A new technique called microangioCT imaging is being used with a novel polymerizing contrast agent that enables 3D visualization of organ vasculature at unprecedented levels.

Tumors may generate millions of Circulating tumor cells per day, but seminal work in cancer biology has established the concept of metastatic inefficiency whereby only a small fraction of these CTCs go on to generate clinically observable metastases.

How to evaluate and compare image quality from different submicrometer CT scans? A simple yet clever test phantom is used for recording 13 scans in a number of commercial and some non-commercial scanners

AutoLV analysis software is the latest addition to VisualSonics robust suite of measurement tools customized for preclinical small animal research.