This Bionano prep SP blood and cell culture DNA isolation kit, can provide ultra-high molecular weight (UHMW) gDNA in less than 4 hours for EDTA-collected blood and mammalian cell cultures.

Bionano’s genome mapping technology directly observes long molecules from 150,000 bp to megabase pair lengths to identify large structural variations typically not detected by short- or long-read sequencing technologies.

The fully automated SageELF (for Electrophoretic Lateral Fractionator) can be used to select DNA or proteins. It features a cassette system designed to fractionate a whole protein or DNA sample simultaneously into 12 contiguous size fractions. 

New isolation protocol for isolating high-quality UHMW DNA from 10 mg of freshly frozen or liquid-preserved animal and human tissue including solid tumors is key to success in optical mapping of long genomic DNA using Bionano Genomics Saphyr system.

Scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets with use the C-trap optical tweezers – fluorescence microscope.

The CATCH process  provides researchers with the most direct access to genes for study. Target regions are defined with the simple design of guide-RNAs to flank regions of interest — and enriched directly from cells.    

The new xxpress thermal cycler has an upgraded optics system that provides better channel separation and enhanced amplification in all five channels. This improvement has been achieved with a new filter set and a new deep red LED for channel 5.