Accelerate to discover

Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for structural varian detection.Several variant calling tools  were evalueted and compared to short-read sequencing.

Aug 16, 2019

Scientific paper
Application

Next-generation cytogenetics is here

On ESHG 2019 conference several oral and poster presentations compared Bionano optical mapping to clinical cytogenetics standard of care in leukemia and constitutional disease testing, and the results surpassed all expectations! 

Aug 9, 2019

Scientific paper
Video

Accelerate your biomedical research

"The CP100NX Ultracentrifuge has proven itself as a reliable and easy-to-use instrument for separation and purification of plant mitochondria and mitochondrial compartments.
It is also successfully used for the isolation of mitochondrial polysomal fractions as well as ribosomes. It has become a truly valuable tool in our work in plant mitochondria biology."

Hanna Janska

University of Wrocław, Department of Cellular Molecualr Biology, Wrocław, Poland

Sage products powering new methods, 2018-19

The fully automated SageELF (for Electrophoretic Lateral Fractionator) can be used to select DNA or proteins. It features a cassette system designed to fractionate a whole protein or DNA sample simultaneously into 12 contiguous size fractions. 

Jun 18, 2019

Scientific paper
Technical breakthrough
Application

The best way to fragment DNA for genomic and paired end library construction

Digilab NextGen Shear DNA Shearing offers the simplest, most reproducible, and most controllable method available for generating random DNA fragments. This software-driven device uses hydrodynamic shearing forces to fragment DNA strands.

Aug 5, 2019

Scientific paper
Technical breakthrough
Application

Identify the quality of any protein in 3 minutes using microliters of sample with Tycho

Tycho tells you so much about the quality of your protein. It tells you about presence, purity, concentration, functionality and similarity — in a single experiment. 

Jul 19, 2019

Technical breakthrough
Application

Accelerate your biomedical research

"We plan to use the Pippin prep for our NGS library purification."

Dr. Jiri Baloun

CEITEC – Central European Institute of Technology, Brno, Czech Republic

Software Update: Bionano releases a new pipeline for low Aalelic fraction SVs

Bionano Solve v3.4 is a major update that introduces an entirely new pipeline to detect SVs at low allelic fraction and an improved copy number tool that calculates fractional copy numbers and calls chromosomal aneuploidy. 

Jul 31, 2019

Scientific paper
Technical breakthrough
Application

Bionano introduce new SP blood and cell culture DNA isolation kit

This Bionano prep SP blood and cell culture DNA isolation kit, can provide ultra-high molecular weight (UHMW) gDNA in less than 4 hours for EDTA-collected blood and mammalian cell cultures.

Jun 26, 2019

Technical breakthrough
Application
Video

New insight into Cas9 off-target activity

Scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets with use the C-trap optical tweezers – fluorescence microscope.

Jun 7, 2019

Application
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