On ESHG 2019 conference several oral and poster presentations compared Bionano optical mapping to clinical cytogenetics standard of care in leukemia and constitutional disease testing, and the results surpassed all expectations! 

The fully automated SageELF (for Electrophoretic Lateral Fractionator) can be used to select DNA or proteins. It features a cassette system designed to fractionate a whole protein or DNA sample simultaneously into 12 contiguous size fractions. 

Digilab NextGen Shear DNA Shearing offers the simplest, most reproducible, and most controllable method available for generating random DNA fragments. This software-driven device uses hydrodynamic shearing forces to fragment DNA strands.

Tycho tells you so much about the quality of your protein. It tells you about presence, purity, concentration, functionality and similarity — in a single experiment. 

Bionano Solve v3.4 is a major update that introduces an entirely new pipeline to detect SVs at low allelic fraction and an improved copy number tool that calculates fractional copy numbers and calls chromosomal aneuploidy. 

This Bionano prep SP blood and cell culture DNA isolation kit, can provide ultra-high molecular weight (UHMW) gDNA in less than 4 hours for EDTA-collected blood and mammalian cell cultures.

Scientists at the MRC London Institute of Medical Sciences and AstraZeneca studied how CRISPR-Cas9 differentiates between on-targets and off-targets with use the C-trap optical tweezers – fluorescence microscope.