The quantitative polymerase chain reaction is the methodology to determine the essential and dominant role of cNEUROG2 gene in the pathogenesis of focal cortical dysplasia (FCD) type II.

We are happy to announce the Bionano Genomics’ 2018 user workshop taking place in San Diego on October 15-16, 2018. Workshop will run all day Monday the 15th and wrap up mid morning on the 16th.

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel disorders of sex development-causing genes and significantly increase total diagnostic yield.

 A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early as 9 weeks gestation using a micro-volume of maternal plasma. 

The new paper describes a chromosome-scale de novo assembly of the repeat-rich Sorghum bicolor Tx430 genome built using Oxford Nanopore sequence combined with Bionano’s Direct Label and Stain optical maps generated on Saphyr.

The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA Fluorescence”,in which authors used the correlative optical tweezers-fluorescence microscopy technology by Lumicks.

We’re pleased to see that PippinHT is featured heavily in the protocol for DNA sizing steps following PCR amplification. Using of an automated size selection instrument like the PippinHT can reduce variability introduced during gel excision.