Accelerate to Discover

Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping

Pulsed-field gel electrophoresis from Sage Science was used for a project to improve sample prep protocols for obtaining high molecular weight DNA from plant cells for optical mapping workflows. 

Jul 20, 2018

Scientific paper
Application

Understanding the pathogenesis of FCD type II using qPCR

The quantitative polymerase chain reaction is the methodology to determine the essential and dominant role of cNEUROG2 gene in the pathogenesis of focal cortical dysplasia (FCD) type II.

Jul 18, 2018

Scientific paper
Application

Accelerate your biomedical research

"We purchased the system as we had a good experience with it in past – our group works in the field of nanomedicine. In experiments, various nanomaterials (carbon, magnetic particles) are modified by antitumor drugs and other molecules for specific targeting of tumor cells.
The the greatest benefit of the system is that the experiments are easy to set up, the data are obtained in a relatively short time without the need for more complicated sample manipulation. The method makes it possible not only to monitor the increasing number of cells, but also to evaluate the progress of this process - to elegantly determine the growth characteristics of the studied cells and to test the substances used. The process is completely independent of the human factor, thereby minimizing common experimental errors."

Prof. René Kizek

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

Real-time verification of clonality using IncuCyte system

Use whole-well, label-free imaging to automatically scan for clones and verify monoclonality. Integrated image processing identifies wells containing emerging colonies, allowing for the rapid identification of clones of interest.

Jun 28, 2018

Technical breakthrough
Application
Product news

B fibers are the best predictors of cardiac activity during Vagus nerve stimulation

Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However, determining stimulus parameters for individual patients is a major challenge.

Jul 17, 2018

Scientific paper
Application

δT cells and CD8+ T cells targeting of breast cancer cells

Cancer stem cells (CSCs) are a large cause of metastasis in breast cancer. They are also very resistent to any effective therapy. In this article, their interaction with δT cells and CD8+ T cells t were studied with Lumascope microscope. 

Jul 11, 2018

Scientific paper
Application

Accelerate your biomedical research

"We currently use the OptiMICE system at the SPF facility of the National Institute of Public Health in  Prague. MICE cages are designed for experimental animal breeding and research, especially infectious models, because it protects the mice among individual cages, and against environmental agents, as well as personnel from animal allergens."

M.D. Anna Fiserova

Czech Technical University in Prague, Kladno, Czech Republic

New technologies to uncover the molecular basis of disorders of sex development

Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel disorders of sex development-causing genes and significantly increase total diagnostic yield.

Jul 13, 2018

Scientific paper
Application

Incucyte system used for generating single-cell-derived cancer-associated fibroblast clones

Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help understand how the heterogeneity of CAFs, which is normal in the body, is affecting the tumour progression.

Jul 9, 2018

Scientific paper
Application

First DLS paper: Sorghum genome assembled with nanopore sequencing and DLS

The new paper describes a chromosome-scale de novo assembly of the repeat-rich Sorghum bicolor Tx430 genome built using Oxford Nanopore sequence combined with Bionano’s Direct Label and Stain optical maps generated on Saphyr.

Jun 26, 2018

Application
Product news

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