The success of immune checkpoint blockade adds new therapeutic category to Cancers are the most heterogenous group of diseases affecting humans. Multiple compensating pathways work to promote disease progression. 

Accurate labeling of endogenous proteins for advanced light microscopy in living cells remains challenging. Nanobodies have been widely used for antigen labeling, visualization of subcellular protein localization andinteractions. 

The ROI shrink‐wrap gives the possibility to automatically generate a region‐of‐interest by adapting to the shape of selected objects and the primitive ROI create an image for the region of interest containing a certain edge as binary object.

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms leading to microvascular occlusion include von Willebrand factor (VWF), notably the formation of ultra-large von Willebrand factor fiber.

RTCA Software Pro is an integrated software package for running and analyzing real time cell analysis data from xCELLigence RTCA DP, SP, and MP instruments. This new version has two modules: RTCA Basic and Immunotherapy.

MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide morphological or metabolic information. However, its inherently low sensitivity remains one of MRI’s major challenges.

An oligo(ethylene glycol)-functionalized squaraine fluorophore has been developed as an NIR-fluorescent probe that can detect and image the activities of a diagnostic enzyme (leucine aminopeptidase) both in vitro and in vivo.