Intravital microscopy can visualize various in vivo cellular-level dynamics such as cell trafficking, cell-to-cell or cell-to-microenvironment interactions in a living animal. Intravital imaging of pathophysiological cellular dynamics in natural in vivo microenvironment in various preclinical animal model can provide an unprecedented insight in the dynamic processes of human diseases beyond conventional histological observation of ex vivo sample or in vitro culture sample.

Immuno-oncology (IO) has transformed cancer treatment. The number of treatments in the IO pipeline continues to increase.  If the treatment is CAR-T cells, adoptive T cell therapy or checkpoint inhibitors, the mechanism of action includes T cell lyse

Understanding how cells organize the array of components within their membranous confines can not only provide insight into essential homeostatic functions it can also shed light on disorganized regions within the cell.

Bacteria and fungi organized into biofilms are highly refractory to known antibiotics and biocides. To develop new solutions to combat biofilms, screening technologies must be designed to grow biofilms under conditions that represent an in vivo or in situ community while maintaining the ability to add and observe the effects of compounds

NanoView Biosciences has developed a unique technology for purification-free analysis of extracellular vesicles and viruses. Exosomes are affinity captured onto a protein microarray (ExoView chip) via common or custom exosomal markers.

We look forward to welcoming many of our users to 2021 PMOD User Meeting. The theme of our PMOD User Meeting will be “Tips & tricks for tracer evaluation and longitudinal studies.”

High resolution micro-CT is being used routinely in science. Mostly it is being used as a substitute to microscopy to look at/for external and internal structures. However, in many cases simply it represents itself, Art.