Accelerate to discover

Back to filter

Related topics

Advancing Alzheimer's disease rsearch with IncuCyte S3 for Neuroscience

Sartorius

Nov 12, 2019

IncuCyte S3 Live-Cell Analysis System for Neuroscience: enables real-time automated measurements of the dynamic changes...

Webinar recording: Analysis of extracellular vesicles by AMNIS imaging flow cytometer

Luminex

Nov 4, 2019

Although conventional flow cytometry is limited to measure small particles down to approximately 300 nm – 500 nm, an...

Targeted mitochondrial DNA extraction and enrichment using the SageHLS

Sage Science

Oct 31, 2019

Sage Science introduced a novel approach for enriching mitochondrial DNA for sequence analysis without PCR or gradient...

Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer at a single low dose

Spectral Instruments Imaging

Oct 24, 2019

Pancreatic ductal adenocarcinoma (PDAC) has been increasing by 0.5% per year in the United States. This study describes...

Nov 13, 2019

New code dedicated to esophageal procedures with Confocal Laser Endomicroscopy

Mauna Kea Technologies

Oct 21, 2019

Announcement of the creation of a new specific procedural code to be added to the Common Classification of Medical...

VisualSonics AutoLV

VisualSonics FujiFilm

Sep 27, 2019

VisualSonics AutoLV allow functional and anatomical analysis of the left ventricle in one click using the power of...

New study resolves helicase dynamics and interactions during DNA replication using C-Trap

LUMICKS

Aug 30, 2019

Researchers from Rockefeller University used a C-Trap optical tweezers – fluorescence microscopy system to observe the...

Nov 13, 2019

Low-dose maging in a new preclinical total-body PET/CT scanner

Bruker Biospin

Aug 28, 2019

Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing...

Show all topics (10)

Co-localization of an antibody-drug conjugate to endosomes or lysosomes

Jun 20, 2016

Using imaging flow cytometry has been possible to optimize an innovative method for studying co-localization of probes by combining the automatic and rapid collection of images with the objective quantification of probe location and intensity.The correlation analysis built in to the IDEAS image analysis software provides robust statistically significant results on large numbers of cells so that phenotypically distinct subsets of cells can be analyzed. In this experiment we use the capabilities of the ImageStreamX system, to measure the transit of a fluorescently labeled antibody-drug conjugate (ADC) through the cellular endocytic pathway. The high spatial resolution afforded by the ImageStreamX system allowed accurate measurement of ADC co-localization to endosomes and lysosomes.

Read more

Scientific paper

Related technologies: Imaging flow cytometry

Get more info

Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Amnis

Amnis has created the ImageStream Cell Analysis System, a breakthrough technology for high speed imaging and analysis of cells in flow.

Related products

Flow cytometer capable of high resoluition microscopic assays

show detail

Combine the speed and statistical power of flow cytometry with microscopy

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey