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A mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection
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Immunophenotyping Extracellular Vesicles using Amnis CellStream
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Four-week individual caging of male ICR mice alters body composition without change in body mass
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Could individual caging affect the physical composition of outbred mice? To investigate this, dual X-ray absorptiometry...
Detect structural variants at 1% allele fraction: Dive deeper into heterogeneous cancer samples
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Insulin receptor substrate 1 is a substrate of the Pim protein kinases
May 18, 2020
The goal of these studies was to identify Pim substrate(s) that could help define the pathway regulated by these...
Jun 20, 2016
Using imaging flow cytometry has been possible to optimize an innovative method for studying co-localization of probes by combining the automatic and rapid collection of images with the objective quantification of probe location and intensity.The correlation analysis built in to the IDEAS image analysis software provides robust statistically significant results on large numbers of cells so that phenotypically distinct subsets of cells can be analyzed. In this experiment we use the capabilities of the ImageStreamX system, to measure the transit of a fluorescently labeled antibody-drug conjugate (ADC) through the cellular endocytic pathway. The high spatial resolution afforded by the ImageStreamX system allowed accurate measurement of ADC co-localization to endosomes and lysosomes.
Related technologies: Imaging flow cytometry
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Amnis has created the ImageStream Cell Analysis System, a breakthrough technology for high speed imaging and analysis of cells in flow.
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