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New technologies to uncover the molecular basis of disorders of sex development
Aug 16, 2018
Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...
Aug 9, 2018
We bring you the latest KOL interview on the Albira Si PET/SPECT/CT from Prof. John Prior, CHUV Lausanne. He describes...
Differentation displacement in acute myeloid leukemia through enhancer activation
Aug 7, 2018
Blast cell differentation is inhibitited by pharmacological targeting of lysine specific demethylase 1 (LSD1). In this...
Aug 3, 2018
Scientists have long been interested in the functional genetic differences that distinguish humans from other ape...
Dynamic PET imaging and special focus in cardiac kinetic analysis
Aug 1, 2018
Micro-computed tomography, or micro-CT, is being employed by a rapidly increasing number of laboratories for bone...
Novel insights on the mechanical properties of IFs using LUMICKS’ technology
Jul 30, 2018
The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from...
Image filtering and Image enhancement
Jul 24, 2018
This issue of Bruker MicroCT Academy is focused on image filtering and enhancement of the picture. Having problems with...
Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping
Jul 20, 2018
Pulsed-field gel electrophoresis from Sage Science was used for a project to improve sample prep protocols for...
Jun 20, 2016
Using imaging flow cytometry has been possible to optimize an innovative method for studying co-localization of probes by combining the automatic and rapid collection of images with the objective quantification of probe location and intensity.The correlation analysis built in to the IDEAS image analysis software provides robust statistically significant results on large numbers of cells so that phenotypically distinct subsets of cells can be analyzed. In this experiment we use the capabilities of the ImageStreamX system, to measure the transit of a fluorescently labeled antibody-drug conjugate (ADC) through the cellular endocytic pathway. The high spatial resolution afforded by the ImageStreamX system allowed accurate measurement of ADC co-localization to endosomes and lysosomes.
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Amnis has created the ImageStream Cell Analysis System, a breakthrough technology for high speed imaging and analysis of cells in flow.
More info at:
www.amnis.com
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