Accelerate to discover

Back to filter

Related topics

Webinar recording: Deep dive into Spatial Biology with MERSCOPE Ultra Platform

Vizgen

Aug 16, 2024

We invite you to learn more about MERSCOPE Ultra Platform. Webinar featuring Rob Mathis (Global Instrument Product...

Single-Cell Genomics applications ? Ideal work for the WOLF gentle cell sorter

NanoCellect

Aug 2, 2024

The field of genomics and computational biology has progressed immensely over the last decade and new single-cell...

Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE

Cellenion

Jul 16, 2024

cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for...

Theranostics: From Mice to Men and Back

MOLECUBES

Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

Oct 4, 2024

Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma

RareCyte

Jun 21, 2024

RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Oct 4, 2024

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Show all topics (10)

“Range+T “ for Tight Sizing of HMW Libraries

May 10, 2024

Sage’s DNA size selection technology has been used to help improve PacBio sequencing, particularly for mammalian and complex genome work since the introduction of the BluePippin (2012). Over the last few years, PacBio®’s Hi-Fi circular consensus sequencing has been the method that has set the gold standard for whole genome sequencing. In terms of library size, this technique benefits greatly from a sharp size cut-off at the LMW end of the size distribution (~10kb) and a slight tail at the HMW end. It also benefits from a narrow fragment size distribution around 17-18kb. A common way to accomplish this is to shear DNA with Diagenode’s Megaruptor®3 device, followed by size selection on a PippinHT or BluePippin.
Range+T is available now for both PippinHT and BluePippin. It requires a software upgrade (v.6.41 and v1.14, respectively, available for download on sagescience/support). We have also packaged cassette kits specifically for this purpose; HRT7510 and BRT7510. Starting Range values can be between 9-30kb.

Read more

Scientific paper
Application

Get more info

Irina Cojocaru

Sales manager

Irina

Cojocaru

+40 749 952 785

Send Message

Brand profile

Sage Science

Preparative electrophoresis systems for targeted size selection of biomolecules.

Related products

Targeted Size Selection for Next-Gen Sequencing (90bp – 50kb)

show detail

Automated size selection for 24 samples at a time.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey