Accelerate to discover

Back to filter

Related topics

Hypoxia in the Tumor Immune Microenvironment (TIME)

Bruker Biospin

Jun 6, 2024

Thursday, 11 July 2024, 16:00 CET | 10:00 EST
Zaver M. Bhujwalla, PhD...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

Bruker Biospin

Jun 4, 2024

MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Spectral Instruments Imaging

Jun 3, 2024

Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM

Jun 18, 2024

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Cell Microsystems

May 27, 2024

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

High-frequency Ultrasound System For Preclinical Imaging


May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies

IVIM Technology

May 8, 2024

Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...

Jun 18, 2024

Minimal information for studies of extracellular vesicles (MISEV2023)


May 7, 2024

MISEV2023 is intended to aid any and all EV researchers: from those just starting their EV journey to more established...

Show all topics (10)

“Range+T “ for Tight Sizing of HMW Libraries

May 10, 2024

Sage’s DNA size selection technology has been used to help improve PacBio sequencing, particularly for mammalian and complex genome work since the introduction of the BluePippin (2012). Over the last few years, PacBio®’s Hi-Fi circular consensus sequencing has been the method that has set the gold standard for whole genome sequencing. In terms of library size, this technique benefits greatly from a sharp size cut-off at the LMW end of the size distribution (~10kb) and a slight tail at the HMW end. It also benefits from a narrow fragment size distribution around 17-18kb. A common way to accomplish this is to shear DNA with Diagenode’s Megaruptor®3 device, followed by size selection on a PippinHT or BluePippin.
Range+T is available now for both PippinHT and BluePippin. It requires a software upgrade (v.6.41 and v1.14, respectively, available for download on sagescience/support). We have also packaged cassette kits specifically for this purpose; HRT7510 and BRT7510. Starting Range values can be between 9-30kb.

Read more

Scientific paper

Get more info

Irina Cojocaru

Sales manager



+40 749 952 785

Send Message

Brand profile

Sage Science

Preparative electrophoresis systems for targeted size selection of biomolecules.

Related products

Targeted Size Selection for Next-Gen Sequencing (90bp – 50kb)

show detail

Automated size selection for 24 samples at a time.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic