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NovoCyte Quanteon - when exceptional performance meets simplicity

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NovoCyte Quanteon system is the answer for growing demands in modern flow-cytometry assays. With its four lasers (405,...

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Early fetal sex determination using micro-volume of maternal plasma

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3R Compliant drug development studies

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In preclinical imaging, magnetic resonance imaging (MRI) can be an attractive alternative to researchers who have...

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Kinase study of cytotoxicity voted paper of the year.

Acea Biosciences

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Society of Toxicology voted a xCELLigence based paper the Paper of the Year. The study of cytotoxicity was done using...

Heterodimeric compounds with dual-targeting active against both HIV and tuberculosis.

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Search for dual action drugs against both HIV and Tuberculosis has lead to the creation of heterodimeric compounds with...

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Method to quantify local force distribution within biomolecular systems

LUMICKS

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The journal Nano Letters has recently published the article “Quantifying Local Molecular Tension Using Intercalated DNA...

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Direct label and stain chemistry is finally here

Apr 3, 2018

Prior to DLS, DNA was labeled using nicking endonucleases to make sequence-specific nicks, which are fluorescently labeled and then repaired. This process is highly robust and specific, but when nick sites were close together on opposite strands it introduced systematic double-stranded breaks that limited the contiguity of Bionano maps.
The DLS chemistry leaves sample DNA intact, eliminating systematic molecule breaks. The DLS protocol consists of a single enzymatic labeling reaction, followed by cleaning and staining. There is no need to repair for a more streamlined protocol.
DLS delivers the best possible genome mapping at a fraction of the cost.

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

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