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New technologies to uncover the molecular basis of disorders of sex development
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δT cells and CD8+ T cells targeting of breast cancer cells
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Incucyte system used for generating single-cell-derived cancer-associated fibroblast clones
Jul 9, 2018
Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help...
Real-time verification of clonality using IncuCyte system
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Use whole-well, label-free imaging to automatically scan for clones and verify monoclonality. Integrated image...
First DLS paper: Sorghum genome assembled with nanopore sequencing and DLS
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Real-time study of platelet formation under sheer-flow with Lumascope
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Platelet formation was observed with Lumascope microscope in a uniform-sheer-flow biorector. Videos of the formation...
Feb 21, 2018
The cytoskeleton and its many molecular motors are major players in a variety of cellular functions. The interconnected networks of cytoskeletal filaments act as tracks directing molecular motor transport and provide structural support and organization to cells. With optical tweezers, we are capable of resolving sub-nanometer displacements and applying pico-Newton forces on single proteins. This force spectroscopy approach has proven extremely useful in elucidating the mechanics and kinetics of molecular motors involved in intracellular transport.
Related technologies: Single-molecule Interactions
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Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics.
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www.lumicks.com
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