Accelerate to discover

Back to filter

Related topics

Saphyr identifies all variants detected by the standard of care in cytogenetics

BioNano Genomics

Jun 1, 2020

Cancer genomics consortium members demonstrate 100% concordance between Bionano Genomics optical mapping technology and...

Immunophenotyping Extracellular Vesicles using Amnis CellStream

Cytek Biosciences

May 29, 2020

Attempts to analyze EVs using traditional PMT- based flow cytometers has been hampered by the limit of detection of...

Four-week individual caging of male ICR mice alters body composition without change in body mass

MEDIKORS

May 25, 2020

Could individual caging affect the physical composition of outbred mice? To investigate this, dual X-ray absorptiometry...

Detect structural variants at 1% allele fraction: Dive deeper into heterogeneous cancer samples

BioNano Genomics

May 22, 2020

To get a complete picture of highly rearranged cancer genomes in heterogeneous samples, use Bionano genome imaging...

Jun 3, 2020

The qNano Gold: Obtain the most detailed Information for each individual nanoparticle

IZON

May 20, 2020

The qNano Gold measures particles using the Tunable Resistive Pulse Sensing (TRPS) principle. TRPS is the most powerful...

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Spectral Instruments Imaging

May 18, 2020

The goal of these studies was to identify Pim substrate(s) that could help define the pathway regulated by these...

Webinar recording: Isolating ultra-high molecular weight (UHMW) DNA for genome analysis

BioNano Genomics

May 12, 2020

Watch the webinar from Bionano Genomics and learn the tips and tricks for isolating high quality UHMW DNA - right from...

Jun 3, 2020

Implementation of Micro CT in CAD/CAM dentistry for image processing and soft computing

Bruker Biospin

May 4, 2020

Present radiology devices are playing an important role in clinical dentistry but their area of application islimited...

Show all topics (10)

In vivo tracking of T cells in an inflammatory Bowel disease mouse model

Jan 16, 2017

Inflammatory Bowel Diseases (IBDs) include Crohn’s disease (CD) and ulcerative colitis (UC). They refer to chronic inflammatory disorders of the intestine and/or the colon. In order to better under stand the roles of T cells in the pathogenesis of IBD, several mouse models are available. In particular, they help get precise information about the initiation, induction and regulation of immunopathology induced by T cells. Here, we explore the potential of Cellvizio imaging for the longitudinal monitoring of T cells in an IBD mouse model. The T cell transfer model is especially used to study Crohn’s disease. It has been instrumental in delineating the immunological mechanisms responsible for the induction and regulation of intest inal inflammat ion. For this model, CD4+CD25- T cells injected to SCID mice can generate within 8 weeks an installed bowel inflammation.

Read more

Scientific paper
Application

Related technologies: Probe based confocal microscopy

Get more info

Miroslav Vecheta

Support specialist

Miroslav

Vecheta

+420 255 700 886

Send Message

Brand profile

Mauna Kea Technologies

Mauna Kea Technologies manufactures Cellvizio Lab, confocal probe based imaging system, providing cellular-level images with minimal invasiveness for longitudinal studies.

Related products

Cellvizio, a fiber based microscope for observing in real time at cellular scale, features simultaneous, co-registered dual band excitation and detection

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey