Accelerate to discover

Back to filter

Related topics

Novocyte 3005 installation in CEMEX Iasi, Romania

Agilent technologies

May 29, 2023

Presentation movie

Recent publication of in-vivo two-photon intravital imaging study targeting mouse kidney

IVIM Technology

May 22, 2023

In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal
formation and
...

Webinar: Multimodal tissue imaging and machine learning to advance precision medicine

RareCyte

May 17, 2023

Join us for this webinar to learn how the Orion spatial biology imaging platform was used to identify prognostic...

Mantis ROI calculator

Formulatrix

May 5, 2023

Decision to improve the output in a lab is always taken based on knowledge and workflow needs. But final decision to...

May 29, 2023

Real-Time and Quantitative Analysis of Macrophage Phagocytosis with RTCA eSight

Agilent technologies

May 4, 2023

The eSight is currently the only instrument that interrogates cell health and behavior using cellular
impedance
...

A deep learning and Monte Carlo based framework for bioluminescence imaging center Maastro

Precision X-Ray

Apr 20, 2023

"In this paper,we developed a framework using deep learning for bioluminescence-based targeting for GBM animal...

Gentle sorting of microbial cells and sub-micron particles using WOLF sorter

NanoCellect

Apr 18, 2023

While most modern applications of flow cytometry may focus on cells of eukaryotic origin, the first flow analyzers were...

May 29, 2023

SPECT imaging properties of the CdTe-Timepix3 detector used in a new prototype

Bruker Biospin

Apr 5, 2023

SPECT (Single Photon Emission Computed Tomography imaging) is one of the most important and widely used methods for the...

Show all topics (10)

Looking for structural variations with IRYS from BioNano Genomics

Mar 15, 2016

Despite recent advances in base-calling accuracy and read length, de novo genome assembly and structural variant analysis using ‘short read’ shotgun sequencing remain challenging. Most resequencing projects rely on mapping the sequencing data to the reference sequence to identify variants of interest. Whole-genome scanning techniques have revealed the prevalence and importance of structural variation. Detecting copy number variation often relies on detection of relative signal intensities by array-based or quantitative PCR-based technologies. However, except for deletions, these methods do not provide positional information regarding the locations of copy number variants, and they cannot detect balanced structural variation, such as inversions or translocations.. The instrumentation presented by BioNano Genomics can improve de novo sequence assembly by providing long labeled DNA contigs with so far unknown structural variations.

Read the application note.

Application

Brand profile

BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

Related products

Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey