Accelerate to discover

Back to filter

Related topics

The draft genome sequence of the Japanese rhinoceros beetle Trypoxylus dichotomus septentrionalis

Sage Science

Nov 30, 2023

The SageHLS instrument was used to size select DNA between 50-80 kb for 10X Genomics Chromium linked read analysis.

Factors Affecting Petri Dish Condensation in Tissue Culture (CU) Chambers

Percival Scientific

Nov 29, 2023

In this report, we will investigate the effects of infrared lighting, light intensity, stacking, as well as constant...

Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals

Luxonus

Nov 28, 2023

With the aid of our uniquely developed device and analysis software, our primary objective is to map the spatial...

A fluorescent reporter system for anaerobic thermophiles

COY laboratory products

Nov 27, 2023

Anaerobic microorganisms are key effectors for the sustainable production of biofuels and biochemicals, as they...

Nov 30, 2023

Vizgen webinar: spatial relationships in Developmental Biology

Vizgen

Nov 21, 2023

MERFISH integrates spatial transcriptomics technology with high resolution spatial imaging, In this webinar we will...

ACCELA educational webinar: Drive key insights and discoveries with new live cell analysis applications for eSight

Agilent technologies

Nov 14, 2023

The xCELLigence RTCA eSight enables simultaneous real time biosensor impedance-based and...

NanoCellect webinar: Plant Potential - Gentle Cell Sorting for Enhanced Plant Biology Workflows

NanoCellect

Nov 3, 2023

Gentle cell sorting is a useful tool to increase the efficiency of plant biology workflows that include gene...

Nov 30, 2023

Single Cell Deposition: the cornerstone of Flow Cytometry for cellular analysis and manipulation

NanoCellect

Nov 2, 2023

One notable technology for harnessing the power of single cell deposition is the NanoCellect WOLF G2 Cell Sorter and N1...

Show all topics (10)

Looking for structural variations with IRYS from BioNano Genomics

Mar 15, 2016

Despite recent advances in base-calling accuracy and read length, de novo genome assembly and structural variant analysis using ‘short read’ shotgun sequencing remain challenging. Most resequencing projects rely on mapping the sequencing data to the reference sequence to identify variants of interest. Whole-genome scanning techniques have revealed the prevalence and importance of structural variation. Detecting copy number variation often relies on detection of relative signal intensities by array-based or quantitative PCR-based technologies. However, except for deletions, these methods do not provide positional information regarding the locations of copy number variants, and they cannot detect balanced structural variation, such as inversions or translocations.. The instrumentation presented by BioNano Genomics can improve de novo sequence assembly by providing long labeled DNA contigs with so far unknown structural variations.

Read the application note.

Application

Brand profile

BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

Related products

Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey