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The Role of Micro-CT in Imaging Breast Cancer Specimens

Bruker Biospin

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The goal of breast cancer surgery is to remove all of the cancer with a minimum of normal tissue, but absence of full...

Bruker´s micro-CT used for some of the World’s First in vivo COVID-19 Imaging Experiments

Bruker Biospin

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Bruker's BioSpin PreClinical Imaging Division reports the use of the Bruker SkyScan 1278 in vivo micro-CT system at the...

A mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection

Spectral Instruments Imaging

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Soft tissue sarcomas pose a significant clinical challenge, with approximately 12,000 new diagnoses and an estimated...

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Attempts to analyze EVs using traditional PMT- based flow cytometers has been hampered by the limit of detection of...

Jul 11, 2020

Four-week individual caging of male ICR mice alters body composition without change in body mass

MEDIKORS

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Could individual caging affect the physical composition of outbred mice? To investigate this, dual X-ray absorptiometry...

Detect structural variants at 1% allele fraction: Dive deeper into heterogeneous cancer samples

BioNano Genomics

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To get a complete picture of highly rearranged cancer genomes in heterogeneous samples, use Bionano genome imaging...

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Spectral Instruments Imaging

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The goal of these studies was to identify Pim substrate(s) that could help define the pathway regulated by these...

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Implementation of Micro CT in CAD/CAM dentistry for image processing and soft computing

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Present radiology devices are playing an important role in clinical dentistry but their area of application islimited...

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Lumicks AFS technology featured in Nature Methods

Jun 1, 2016

The novel method of using acoustics for single molecule manipulation and spectroscopy was published in Nature methods.

Force spectroscopy has become an indispensable tool to unravel the structural and mechanochemical properties of biomolecules. Here we extend the force spectroscopy toolbox with an acoustic manipulation device that can exert forces from subpiconewtons to hundreds of piconewtons on thousands of biomolecules in parallel, with submillisecond response time and inherent stability. This method can be readily integrated in lab-on-a-chip devices, allowing for cost-effective and massively parallel applications.

LUMICKS is already offering two versions of its commercial solution for AFS, namingly the AFS module that can be mounted on any inverted microscope, and the AFS stand-alone system with particle tracking.

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Scientific paper

Related technologies: Single-molecule Interactions

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LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

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Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

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