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Webinar : meet the Cytek's new cFluor reagents

Cytek Biosciences

Jan 25, 2021

Cytek Biosciences has already redefined what is possible in flow cytometry. The new Cytek cFluor family of reagents...

STAT Protein Phosphorylation in CD4+ T Cells using the CellStream flow cytometer

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Cytokine-induced protein phosphorylation is a key cell signaling event within the immune system that modulates diverse...

Introducing Cytek cFluor, 14 Colors Immunoprofiling Kit

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A Glimpse on physiological monitoring for the in vivo SKYSCAN Systems

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This past year has proven once again that in vivo imaging is an important aspect in the microCT world. For longitudinal...

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Cytek full Spectrum flow Cytometry webinar: Part II – panel design and troubleshooting

Cytek Biosciences

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In this session, we will continue to look at full spectrum flow cytometry and look at considerations for fluorescence...

CQ1 webinar : optimizing high-content imaging of 3D models for drug discovery

Yokogawa

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In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their...

IncuCyte for in-vitro analysis of SARS-CoV-2 vaccine candidate

Sartorius

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Watch this video to learn how researcher at Humane Genomics are utilizing the Incucyte platform for the in-vitro...

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Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

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Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have...

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Mutual destruction of deep Lung tumor tissues by nanodrug‐conjugated and CQ1 imaging cytometer

Jun 1, 2018

The 10‐year survival rate of cancer patients has greatly increased over the last 20 years. However, the survival rate of patients with major malignant tumors, such as lung and pancreatic cancers, still shows negligible improvement.The conventional chemotherapeutic strategy for treating lung cancer remains unsatisfactory in this respect. Specifically, the 5‐year survival rates of both non‐small‐cell lung cancer (NSCLC) and small cell lung cancer (SCLC) patients exhibited merely 4–5% improvements in the past decade for cancer in stages I–III.2 The main difficulty in treating lung cancer is the lack of targeted chemotherapeutic agents specific to the lung tumor tissues and, thus, non‐specific targeting generally leads to unwanted side effects induced by excessive doses of chemotherapeutic agents.

Several strategies have been introduced to resolve the aforementioned issues, such as cancer antigen‐targeted monoclonal antibody (mAb) therapy,4 nanodrug delivery,5 and cell‐mediated therapy (i.e., T‐cell‐based therapy for NSCLC6). However, many clinical trials have shown that intravenously administered mAb, particularly epidermal growth factor receptor‐targeting mAbs, induced dermatological toxicities (e.g., acneiform eruption, xerosis, telangiectasia, hyperpigmentation, fissures, and hair/nail changes) in over 50% of patients after treatment.

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Yokogawa is a leading provider of confocal quantitative live cell imaging platforms. Combining superior technology with engineering services, project management, and maintenance, Yokogawa delivers field proven operational efficiency, safety, quality, and reliability. 

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