Accelerate to discover

Back to filter

Related topics

Improved differentiation of Retinal Organoids stem cells derived using rotating-wall vessels

Synthecon

Jan 15, 2019

Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a...

IncuCyte webinar recording: CAR T-cell therapy, frontiers in cancer Immunotherapy

Sartorius

Jan 11, 2019

The success of immune checkpoint blockade adds new therapeutic category to Cancers are the most heterogenous group of...

CT‐analyzer plug‐ins: ROI shrink‐wrap and primitive ROI

Bruker Biospin

Jan 7, 2019

The ROI shrink‐wrap gives the possibility to automatically generate a region‐of‐interest by adapting to the shape of...

Cytek Aurora spectral flow cytometer - say hello to a new reality

Cytek Biosciences

Jan 7, 2019

A prodigy that takes flow cytometry to the next level of performance and flexibility. With up to four lasers, three...

Jan 16, 2019

ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications

Acea Biosciences

Dec 28, 2018

RTCA Software Pro is an integrated software package for running and analyzing real time cell analysis data from...

Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

Dec 19, 2018

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...

The need for ultra high field magnetic resonance imaging

Bruker Biospin

Dec 17, 2018

MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

Jan 16, 2019

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies

Etaluma

Dec 6, 2018

Accurate labeling of endogenous proteins for advanced light microscopy in living cells remains challenging. Nanobodies...

Show all topics (10)

Neuronal co-culture imaging

Aug 11, 2016

Neurite dynamics play a fundamental role in the development and function of the nervous system. Formation and maintenance of synaptic networks are necessary for nervous system function and plasticity through continuous changes in the fine structure of neurons. Neurite dynamics can be altered in disease states or following exposure to neurotoxic agents providing a rationale for understanding and quantifying this process.

The IncuCyte ZOOM live-cell imaging platform, combined with NeuroTrack software and the NeuroLight Red labeling reagent, provides a means to image neurons in co-culture with astrocytes and quantitate changes in neurite length of living cultures from days to weeks. This approach provides a sensitive method to detect pharmacological manipulations that alter neurite dynamics, including processes such as elongation and retraction. NeuroLight Red can be used with multiple neuronal types providing flexibility in assay design. The NeuroPrime Cell Kit, in conjunction with the NeuroTrack software module, also provides a ready to use and optimized solution for measuring kinetic changes in neurite length using primary neurons. The imaging strategy allows all quantitative data to be validated by direct comparison with morphological changes in the images, allowing a uniquely thorough analysis in a single assay.

Application
Product news

Brand profile

Sartorius

Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. We invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey