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Theranostics: From Mice to Men and Back

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Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

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Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Use of MRI and microCT to evaluate gene therapy for the treatment of discogenic back pain

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MRI images were obtained using the 9.4T Bruker BioSpec system, equipped with 40 mm 1H quadrature volume resonator, and...

High-frequency Ultrasound System For Preclinical Imaging

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The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

Jul 22, 2024

“Range+T “ for Tight Sizing of HMW Libraries

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We decided to do a deep dive into Range+T to get a better handle the method, and to develop best practices for using...

April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies

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Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...

Minimal information for studies of extracellular vesicles (MISEV2023)

IZON

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RainDrop Digital PCR system provides lower limit of detection down to 1 > 1 million

Mar 22, 2016

For many assays, dPCR sensitivity is significantly higher than traditional PCR analysis, and the accuracy and precision of the assay improves by counting larger numbers of molecules individually. The sensitivity of digital PCR will facilitate detection limits that redefine our understanding of disease onset, progression, and recurrence. One particularly attractive application of digital PCR is the quantitative detection of a small number of mutated DNA molecules among a large number of wild-type molecules, which is relevant to cancer research, and especially for the detection of minor alleles. Cancerous tissue is often highly heterogeneous and cancer biomarkers vary across types of disease and stages of disease progression which complicates cancer detection and identification at early stages. The RainDrop dPCR System within its droplets productivity offers outstanding performance regarding lower limit of detection. 

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RainDance Technologies

RainDance company’s ultra-sensitive genomic tools enable research of novel non-invasive liquid biopsy applications that should result in more accurate, reliable, cost-effective, and early detection of cancer and other inherited and infectious diseases.

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Capable of generating more than a billion reactions in a single day, the RainDrop system surpasses all existing technologies and establishes a new performance standard in sensitivity, quantitation and multiplexing.

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