Accelerate to discover

Back to filter

Related topics

Webinar recording: Isolating ultra-high molecular weight (UHMW) DNA for genome analysis

BioNano Genomics

May 12, 2020

Watch the webinar from Bionano Genomics and learn the tips and tricks for isolating high quality UHMW DNA - right from...

Isoflux webinar: Accurate liquid biopsy approach reveals mutations in lung cancer patients

Fluxion Biosciences

Apr 29, 2020

Liquid biopsies aim to identify clinically actionable information from cell-free DNA (cfDNA) and circulating tumor...

Panel design principles to investigate COVID-19 immune response with the Cytek Aurora

Cytek Biosciences

Apr 27, 2020

Learn about the Cytek Aurora and panel design tools available to help you design high quality full spectrum cytometry...

Ensuring Quantitative Accuracy in PET webinar

Bruker Biospin

Apr 14, 2020

Image quality is only one aspect of functional imaging with PET and SPECT and the ability to reproducibly extract...

May 26, 2020

xCELLigence system: rapid and sensitive, ideal for infectious viral assays.

Acea Biosciences

Mar 30, 2020

As the public health threat from COVID-19 and future emergent viruses continue to persist, the rapid, sensitive, and...

IncuCyte webinar: Organoids, iPSCs, and advanced cell models.

Sartorius

Mar 24, 2020

Researchers are now moving from reductionist, 2D monoculture assay models to more complex 3D cell models, such as...

Webinar recording: Metabolic MR Imaging of Obesity

Bruker Biospin

Mar 24, 2020

The study of fat distribution is important to understand the pathophysiology of obesity related disorders, diabetes...

May 26, 2020

Webinar recording: Ex vivo microangioCT, advances in microvascular imaging

Bruker Biospin

Mar 16, 2020

A new technique called microangioCT imaging is being used with a novel polymerizing contrast agent that enables 3D...

Show all topics (10)

Real-time analysis of cellular phagocytosis - Tuesday, June 20, 2017, 5 pm CEST

Jun 1, 2017

Tim Dale, Director of Biology, Europe, Essen BioScience

Alongside intense efforts to exploit T-cells as immunotherapies for cancer (e.g. checkpoint inhibitors, CAR-T, T-cell metabolism), researchers are increasingly considering other immune cell types for novel targets. One example is the enhancement of macrophage function via inhibitors of CD47 “don’t-eat-me” signalling proteins, enabling tumour cells to evade clearance by neighbouring phagocytes (Kim et al, 2012, Leukemia 26, 2538–2545). To identify new CD47 and phagocyte modulators, novel, direct and validated assays with throughput commensurate to drug discovery are required.

In this mini-webinar Tim Dale will:

-Illustrate how real-time live-cell analysis using pH-sensitive fluorescent probe-labelled target cells can be used to visualize and quantify phagocytosis.
-Share data on the pro-phagocytic effects of anti-CD47 antibodies.
-Demonstrate how other live-cell phenotypic assays (e.g. apoptosis, proliferation) are used to validate mechanisms of action.

Register now

Webinar

Get more info

Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Sartorius

Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. We invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.

Related products

High throughput, real-time and automated measurements of live-cell activity, inside your incubator

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey