Accelerate to discover

Back to filter

Related topics

Real-time and quantitative analysis of Macrophage Phagocytosis with RTCA eSight

Agilent technologies

Feb 23, 2024

The eSight is currently the only instrument that interrogates cell health and behavior using cellular
impedance
...

Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

Luxonus

Feb 21, 2024

In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

Therapeutic effects of mesenchymal stem cells in myocardial infarction

S-Sharp

Feb 19, 2024

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem...

Whole-slide biomarker quantitation in 82-patient NSCLC cohort study of acquired resistance to PD-(L)

RareCyte

Feb 7, 2024

Samples from 82 patients with NSCLC and matched pre- and post-ICI biopsies were subjected to genomic profiling and to...

Mar 4, 2024

Improve your data resolution with Cytek Autofluorescence Extraction tool!

Cytek Biosciences

Feb 5, 2024

Samples with high autofluorescence (AF) can be difficult to resolve with conventional flow cytometry, especially if...

Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice

Spectral Instruments Imaging

Jan 17, 2024

Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity

Application of focal X-ray irradiation in canaries

Precision X-Ray

Jan 15, 2024

Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries

Mar 4, 2024

Radiation planning for image guided preclinical radiotherapy

Precision X-Ray

Jan 12, 2024

Doctoral Thesis, Stefan van Hoof, Maastricht University 2019

Show all topics (10)

Tina Graves webinar - challenges faced in human whole genome assembly

May 4, 2016

Traditionally, generating a whole-genome physical or genetic map has been one of the first steps in exploring genomes. Long-range information is crucial to the accurate understanding of relationships between functional elements in the genome and making sense of more detailed follow-on experiments.
Many current high-throughput genomic technologies start by fragmenting and amplifying DNA. This necessity often sacrifices vital long-range connectivity, causing researchers to miss many structural variants, including rearrangements, inversions and copy-number variants, which lead to inaccurately sized gaps.

Genome maps can contribute greatly to improving contiguity, accurately identifying gaps and revealing missed structural variation, even after a substantial amount of sequencing has been conducted. To achieve higher-quality genome analysis and comprehensive views of variation, a complete genome map is essential.

Tina Graves will describe how she has used the Irys genome maps to improve the CHM1 single haplotype human whole genome assembly. These genome maps have helped discover assembly errors, size gaps and confirm previously unsure regions of the assembly.

VIEW WEBINAR

Application
Webinar

Brand profile

BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

Related products

Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey