Accelerate to discover

Cell plasticity associated to circulating tumor cells from prostate cancer patients

Treatment resistance is associated with tumor cells molecular plasticity. In metastatic castration resistant prostate cancer (mCRPC), alterations in androgen receptor (AR) have been described as predictors of shorter response to hormonal treatments.

Mar 13, 2019

Scientific paper
Application

Enhanced uptake of luminescent quantum dots by live cells

The steady progress made over the past threedecades in growing a variety of inorganic nanomaterials, with discreet control over their size and photophysical properties,has been exploited to develop several imaging and sensing applications.

Mar 1, 2019

Scientific paper
Application

Accelerate your biomedical research

"The course prepared by accela for a flow cytometer NovoCyte, ACEA was really helpful and interesting, showing how easy can be working with cells and particle solutions. The staff of accela is well organized so the course was prepared perfectly. At the moment, I´m convinced to use the instrument in my research."

Ewa Moliszewska, PhD,

Opole University, Opole, Poland

Responsive fluorescence probe for detection of Hypochlorous acid in live cells and animals

In this work, a new fluorescence probe, PQI, was developed for monitoring of the HOCl level in biological samples. The fluorescence of PQI was found to be significantly increased, leading to “OFF‐ON” fluorescence response towards HOCl.

Jan 17, 2019

Scientific paper
Application

Fat-water separation Imaging in Preclinical MRI

Non-invasive in vivo phenotyping of adipose tissue deposits in small animal models is of great importance in preclinical metabolic research. In MRI, fat suppression is often performed to avoid artifacts arising from fat.

Mar 1, 2019

Scientific paper
Application

Small animal 13C-hyperpolarized MRI

13C-Hyperpolarized molecules provide a unique signature for molecular processes relevant to a range of disease processes that can be imaged by MRI and promises improved detections for certain indications relative to traditional molecular imaging

Feb 8, 2019

Scientific paper
Application

Accelerate your biomedical research

"I was very pleased to have the opportunity to work with the Lumascope, a compact microscope with very powerful autofocus that can fit in standard cell culture incubator, easily accessible for objective exchange.  Fluorescent measurement showed high quality of pictures taken with crisp fluorescent signal, enabling to distinguish GFP labeled mitochondria using 40x lens. High definition phase contrast module enable also label free cell proliferation. Thus, the system would be definitely a great asset to test the effect of compounds on proliferation and morphology changes". 

Dr. Jaroslav Truksa

BIOCEV, Vestec, Czech Republic

New technique for dynamic monitoring of liquid tumor Cytotoxicity

To develop and validate immuno-oncology therapies, scientists must understand the full dynamics of cytotoxic effectors in action as well as the destruction of target tumors.

Feb 12, 2019

Scientific paper
Application

Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts

Pancreatic ductal adenocarcinoma has been increasing by 0.5% per year in the United States. This study describes the generation and characterization of a novel oncolytic chimeric orthopoxvirus for the treatment of pancreatic cancer.

Jan 30, 2019

Scientific paper
Application

Improved differentiation of Retinal Organoids stem cells derived using rotating-wall vessels

Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a polarized, laminated architecture. In static cultures, organoid development may be hindered by limitations in diffusion of oxygen.

Jan 15, 2019

Scientific paper
Application
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