Accelerate to discover

PET/CT Si78: Versatility in microCT dose, speed, & resolution

The Bruker PET/CT Si78 now pairs total-body PET and SkyScan microCT technology. This combination offers the advanced microCT features of SkyScan for a high-speed/low-dose PET anatomical reference.

May 9, 2019

Scientific paper
Product news

Cell by cell lung cancer marker profiling using high-parameter spectral flow cytometry

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80-85% cases of lung cancer. It has poor prognosis as most NSCLC patients are at advanced stage when diagnosed.

May 2, 2019

Scientific paper
Application

Accelerate your biomedical research

"The X-RAD 225XLi Biological Irradiator allows us to deliver collimated, focused x-ray irradiation to mice and the built-in OptiMAX M-IGRT imaging module enables us to get high-resolution
X-ray and optical multimodal images."

Dr. Géza Sáfrány

Department of Radiobiology and Radiohygiene, National Public Health Institute, Budapest, Hungary

Spectral flow cytometric analysis of loss-of-function mutations in granular cell tumors

Granular cell tumors (GCTs) are rare tumors that can arise in multiple anatomical locations,and are characterized by abundant intracytoplasmic granules. The genetic drivers of GCTsare currently unknown.

Mar 29, 2019

Scientific paper
Application

In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model

As a trace element nutrient, cobalt is critical for both prokaryotes and eukaryotes. In the current study, a turn-on Cobalt Bioluminescent Probe for the detection of cobalt has been successfully developed based on oxidative C–O bond cleavage.

Apr 26, 2019

Scientific paper
Application

Novel imaging-based assay for hERG channel inhibition using iPS-derived Cardiomyocytes

A large percentage of drugs fail in clinical studies due to cardiac toxicity, such as drug-induced QT prolongation.Therefore,acute and direct inhibition of hERG is routinely assessed in preclinical studies.

Apr 4, 2019

Scientific paper
Application

Accelerate your biomedical research

“Our Arabidopsis as well as other plants look contented and we appreciate their health.”

Dr. Alexandra Husičková

Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic

Synthesis and characterization of functional nanofilm-coated live Immune cells using CQ1

Layer-by-layer assembly techniques have been extensively studied in cell biology because of their simplicity of preparation and versatility. The applications of the LbL platform technology using polysaccharides, silicon and graphene have been studied

Apr 10, 2019

Scientific paper
Application

Modified Beta-carotene-bound albumin nanoparticles for breast tumor ablation

The albumin nanoparticles were fabricated using a beta-carotene cross-linker via the Nab technique. These new albumin nanoparticles would be potential as a photodynamic antitumor agent for breast cancers.

Mar 29, 2019

Scientific paper
Application

Cell plasticity associated to circulating tumor cells from prostate cancer patients

Treatment resistance is associated with tumor cells molecular plasticity. In metastatic castration resistant prostate cancer (mCRPC), alterations in androgen receptor (AR) have been described as predictors of shorter response to hormonal treatments.

Mar 13, 2019

Scientific paper
Application

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