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Charting the dark matter of cancer genomes

Nov 6, 2017

Host Theral Timpson asks Dr. Broach on the mendelspod podcast to discuss his use of new technologies like Bionano Genomics' optical maps to answer the question, why does cancer arise, and how do we treat it? They also discuss how important structural variation will be in cancer diagnosis.  How sequencing is necessary, but not sufficient for studying large SV. How quickly could optical mapping replace traditional karyotyping and is it already a cost effective substitute?

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

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