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B fibers are the best predictors of cardiac activity during Vagus nerve stimulation

VisualSonics FujiFilm

Jul 17, 2018

Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However,...

New technologies to uncover the molecular basis of disorders of sex development

BioNano Genomics

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Newer approaches, such as whole-genome sequencing and whole-genome mapping have the potential to identify novel...

δT cells and CD8+ T cells targeting of breast cancer cells

Etaluma

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Cancer stem cells (CSCs) are a large cause of metastasis in breast cancer. They are also very resistent to any...

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Single-cell-derived cancer-associated fibroblast (CAFs) were produced using Incucyte. These cells were used to help...

Jul 18, 2018

Real-time study of platelet formation under sheer-flow with Lumascope

Etaluma

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Platelet formation was observed with Lumascope microscope in a uniform-sheer-flow biorector. Videos of the formation...

Early fetal sex determination using micro-volume of maternal plasma

BJS Biotechnologies

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 A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early...

3R Compliant drug development studies

Bruker Biospin

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In preclinical imaging, magnetic resonance imaging (MRI) can be an attractive alternative to researchers who have...

Jul 18, 2018

Kinase study of cytotoxicity voted paper of the year.

Acea Biosciences

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Society of Toxicology voted a xCELLigence based paper the Paper of the Year. The study of cytotoxicity was done using...

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De novo sequence assembly using nanochannel arrays from BioNano Genomics

Apr 4, 2016

Next-generation sequencing (NGS) technologies have enabled high-throughput and low-cost generation of sequence data;however, de novo genome assembly remains a great challenge, particularly for large genomes. NGS short reads are often insufficient to create large contigs that span repeat sequences and to facilitate unambiguous assembly. Plant genomes are notorious for containing high quantities of repetitive elements, which combined with huge genome sizes, makes accurate assembly of these large and complex genomes intractable thus far. Using two-color genome mapping of tiling bacterial artificial chromosomes (BAC) clones on nanochannel arrays delivered by BioNano Genomics, scientists completed high-confidence assembly of a 2.1-Mb, highly repetitive region in the large and complex genome of Aegilops tauschii.

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Scientific paper

Related technologies: Genome Mapping

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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