Accelerate to discover

Back to filter

Related topics

ACCELA educational webinar: Unlocking Spatial Biology with RareCyte Orion

RareCyte

Mar 16, 2023

Experience Spatial Biology with Orion Multiplex Imaging. Orion is a benchtop, high...

Recorded webinar: Anesthesia Considerations in Small Animal Imaging

Spectral Instruments Imaging

Mar 13, 2023

Anesthesia settings and operation of Optical Imaging Systems: methods, animal handling, safety and regulatory...

Introducing Cytek Human Leukocyte Kit, the first ever 15-color lyse no-wash assay

Cytek Biosciences

Mar 13, 2023

This kit has been designed to enumerate all major leukocyte subsets and it mirrors and expands on those identified in a...

Immunofluorescence Imaging for Rare Cell Detection with CyteFinder II

RareCyte

Mar 7, 2023

CyteFinder II Instruments are high speed, whole slide imaging systems with options for liquid biopsy analysis and...

Mar 24, 2023

NanoCellect Webinar: Optimizing the Cell Line Development Process with Microfluidic Cell Sorting

NanoCellect

Mar 3, 2023

Single-cell selection and cloning are required for bioengineering workflows such as antibody production, cell therapy,...

New Kit for Bacterial analysis expands capability of Guava Muse flow cytometer

Luminex

Feb 20, 2023

With the Guava Muse cell analyzer, you can now achieve highly quantitative results at a fraction of the price, effort,...

Flash news - did you know, that you can use Singulator S100 also for plant research?

S2 Genomics

Feb 10, 2023

In this short TechNote you can find how Singulator can help the data quality in Single cell sequencing - now even in...

Mar 24, 2023

Webinar: Spatial Biology and immunofluorescence to study human pancreata in in type 1 diabete

RareCyte

Feb 9, 2023

In this webinar, Dr. Quesada-Masachs from La Jolla Institute for Immunology reveals the image analysis pipeline that...

Show all topics (10)

Improved differentiation of Retinal Organoids stem cells derived using rotating-wall vessels

Jan 15, 2019

Herein, scientists report a bioprocess using Synthecon rotating-wall vessel (RWV) bioreactors to culture retinal organoids derived from mouse pluripotent stem cells. Organoids in RWV demonstrate enhanced proliferation, with well-defined morphology and improved differentiation of neurons including ganglion cells and S-cone photoreceptors. Furthermore, RWV organoids at day 25 (D25) reveal similar maturation and transcriptome profile as those at D32 in static culture, closely recapitulating spatiotemporal development of postnatal day 6 mouse retina in vivo. Interestingly, however, retinal organoids do not differentiate further under any in vitro condition tested here, suggesting additional requirements for functional maturation. Studies demonstrate that bioreactors can dramatically accelerate and improve organoid growth and differentiation for modeling retinal disease and evaluation of therapies.

Read the whole paper!

 

Scientific paper
Application
Video

Related technologies: 3D cell culturing

Get more info

Riccardo Pasculli

Head of application support

Riccardo

Pasculli

+420 731 127 717

Send Message

Brand profile

Synthecon

Inovating 3D cell culture technology exploring the rotary culture system for tissue engineering, stem cell, tumor spheroid and more. Unique Rotary Cell Culture System (RCCS)  for 3D culturing both suspension and anchorage-dependent cells.

Related products

The disposable (single use) vessel culture systems are low cost, easy to use, rotary bioreactor systems that utilize disposable culture vessels to enable 3D cell culture.

show detail

The autoclavable RCCS use culture vessels designed for repeated autoclaving, and ideal for long-term use. Suitable for any of the Synthecon culture vessels supplied with variable speed motor drives equipped with tachometer.

show detail

RCCMAX allows undisturbed 3D cultivation of cells in vitro condition with continuous supplementation of fresh media and oxygen.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey