Accelerate to discover

Back to filter

Related topics

Cytek Biosciences hits flow cytometry milestone: 40 color analysis from a single sample

Cytek Biosciences

Oct 17, 2019

Cytek Aurora turning aspirations into realizations: 40 Colors, One Tube. Until recently, developing fluorescence-based...

Vascular imaging using a contrast-enhanced microCT approach

Bruker Biospin

Oct 14, 2019

Are you interesting in MicroangioCT? Do you heard about Vascular imaging using a contrast-enhanced microCT approach?...

Change the way you process cells with Curiox Laminar Wash systems

Curiox

Oct 8, 2019

Laminar Wash technology is for scientists who believe that quantitative flow cytometry is critical to cell therapy,...

Acquisition and analysis of reproducible high-complexity cytometry data using the Cytek Aurora

Cytek Biosciences

Oct 8, 2019

We invite you to join us on Friday, October 11 at 8:00 PM CET to hear more about Cytek collaborative...

Oct 21, 2019

Webinar recording - Highly sensitive structural variant detection for medical genetics

BioNano Genomics

Oct 4, 2019

Follow the webinar outlining how a team at Radboud University Medical Center is assessing ultra-long read optical...

Cytek users evening forum

Cytek Biosciences

Sep 30, 2019

Enjoy an evening to meet with Cytek technical application specialists and technical sales representatives and share...

VisualSonics AutoLV

VisualSonics FujiFilm

Sep 27, 2019

VisualSonics AutoLV allow functional and anatomical analysis of the left ventricle in one click using the power of...

Oct 21, 2019

Unlimited capabilities of IncuCyte system: discover the latest Cell Cycle assays

Sartorius

Sep 23, 2019

The IncuCyte Cell Cycle Assay combines easy-to-learn automated image acquisition and integrated analysis of 96- or...

Show all topics (10)

Linked-read sequencing combined with optical mapping produce a high quality mammalian genome

Sep 18, 2017

Current short-read methods have come to dominate genome sequencing because they are cost-effective, rapid, and accurate. However, short reads are most applicable when data can be aligned to a known reference. Two new methods for de novo assembly are linked-reads and restriction-site labeled optical maps. We combined commercial applications of these technologies for genome assembly of an endangered mammal, the Hawaiian monk seal. We show that the linked-reads produced with 10X Genomics Chromium chemistry and assembled with Supernova v1.1 software produced scaffolds with an N50 of 22.23 Mbp with the longest individual scaffold of 84.06 Mbp. When combined with Bionano Genomics optical maps using Bionano RefAligner, the scaffold N50 increased to 29.65 Mbp for a total of 170 hybrid scaffolds, the longest of which was 84.78 Mbp. These results were 161X and 215X, respectively, improved over DISCOVAR de novo assemblies.

Read more

Scientific paper
Technical breakthrough
Application

Related technologies: Genome mapping

Get more info

Regina Fillerová

Field application specialist

Regina

Fillerová

+420 731 127 718

Send Message

Brand profile

BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

Related products

Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

show detail

Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey