Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
Automated microscopy and Spatial Proteomics
Real-time, label free cell analysis
Nano and micro particle analysis
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The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging
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Here, we assessed the chicken chorioallantoic membrane (CAM) as an alternative to mice for preclinical cancer imaging...
A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence
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A thrombin-responsive and fixed-point cleaved Fu@pep-CLipo was developed for highly efficient and precise thrombolysis...
A 19-color single-tube Full Spectrum Flow Cytometry for the detection of Acute Myeloid Leukemia
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This recent publication in Cytometry Part A describes the development and comprehensive workflow of a single-tube,...
18F-labeled somatostatin analogs for somatostatin receptors (SSTRs) targeted PET imaging of NETs
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A novel 18F-radiolabeled somatostatin analogue, [Al18F]NODA-MPAA-HTA, was synthesized and evaluated for positron...
Discover Yokogawa CellVoyager CQ1: Benchtop High-Content Analysis System
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Unlike flow cytometers, the CellVoyager CQ1 confocal quantitative image cytometer does not require pretreatment such as...
Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System
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In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...
Therapeutic effects of mesenchymal stem cells in myocardial infarction
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Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice
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Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity
Monitoring the formation and removal of biofilms from clinically relevant pathogens in real-time
Apr 3, 2017
A large percentage of bacterial species are capable of growing on biotic and abiotic surfaces. Within these surfaced-adhered communities secreted signaling molecules are used to coordinate gene expression across the entire colony, thereby promoting survival. An adaptation commonly found within these colonies is the production of biofilm, a secreted extracellular polymeric matrix that can be comprised of polysaccharides, nucleic acids, proteins, lipids, and/or teichoic acids. This extracellular matrix increases bacterial virulence by acting as a physical barrier that both occludes antibiotic molecules and helps the bacteria to evade detection by immune cells. Bacterial biofilms are of great importance to human health, causing dental plaque and caries, chronic infections, food poisoning, and rejection of implants. Despite the growing prevalence of biofilm infections, the existing arsenal of antibiotics for treating them is limited.
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