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Structural variants identified by Oxford Nanopore PromethION sequencing of the human genome

Sage Science

Aug 16, 2019

The BluePippin was used for High Pass DNA size selection prior to library construction. ONT Promethion was used for...

Next-generation cytogenetics is here

BioNano Genomics

Aug 9, 2019

On ESHG 2019 conference several oral and poster presentations compared Bionano optical mapping to clinical cytogenetics...

Electroporation using Lumascope: A sustainable method for Adipogenous Mesenchymal Stem Cells

Etaluma

Aug 7, 2019

Human mesenchymal stem cells derived from adipose tissue (AD-hMSCs) represent a promising source for tissue engineering...

The best way to fragment DNA for genomic and paired end library construction

Digilab

Aug 5, 2019

Digilab NextGen Shear DNA Shearing offers the simplest, most reproducible, and most controllable method available for...

Aug 19, 2019

Software Update: Bionano releases a new pipeline for low Aalelic fraction SVs

BioNano Genomics

Jul 31, 2019

Bionano Solve v3.4 is a major update that introduces an entirely new pipeline to detect SVs at low allelic fraction and...

On-cartridge preparation and evaluation of 68Ga-, 89Zr- and 64Cu-precursors for cell radiolabelling

Bruker Biospin

Jul 29, 2019

Method of on-cartridge formation of gallium-68, zirconium-89 and copper-64 complexes in small volumes suitable for cell...

CQ1 confocal quantitative image cytometer: fighting colon cancer with killer cells

Yokogawa

Jul 2, 2019

Genetically modified immune cells can successfully destroy colon cancer cells. This has been demonstrated for the first...

Aug 19, 2019

Breast cancer‐derived exosomes reflect the cell of origin phenotype

IZON

Jun 24, 2019

The qNano Gold measures particles using the Tunable Resistive Pulse Sensing (TRPS) principle. TRPS is the most powerful...

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Monitoring the formation and removal of biofilms from clinically relevant pathogens in real-time

Apr 3, 2017

A large percentage of bacterial species are capable of growing on biotic and abiotic surfaces. Within these surfaced-adhered communities secreted signaling molecules are used to coordinate gene expression across the entire colony, thereby promoting survival. An adaptation commonly found within these colonies is the production of biofilm, a secreted extracellular polymeric matrix that can be comprised of polysaccharides, nucleic acids, proteins, lipids, and/or teichoic acids. This extracellular matrix increases bacterial virulence by acting as a physical barrier that both occludes antibiotic molecules and helps the bacteria to evade detection by immune cells. Bacterial biofilms are of great importance to human health, causing dental plaque and caries, chronic infections, food poisoning, and rejection of implants. Despite the growing prevalence of biofilm infections, the existing arsenal of antibiotics for treating them is limited.

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Scientific paper

Related technologies: Real-time, label free cell analysis

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Riccardo Pasculli

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Acea Biosciences

ACEA manufactures xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

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Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

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