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Build your experiments online with new Spectrum Viewer and SpectroFlo Experiment Builder

Cytek Biosciences

May 5, 2021

Explore new capabilities of Cytek's Full Spectrum Viewer and complementary SpectroFlo Experiment Builder. Explore on...

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Anesthesia is just a complex technique in which the administration of anesthetics drugs is the less important step.

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Cytek webinar : Evaluating Spectral Cytometry for Immune Profiling in Viral Disease

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The impact of environmental Oxygen content on Natural Killer Cell Immunotherapy

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New scientific article using Attana Biosensors

Jun 1, 2016

A novel method for facile fabrication of glycopolymer-based iron oxide nanoparticles (GIONs) is developed.                                   Via perfluorophenylazide photochemically induced C–H insertion, alkynyl groups were introduced onto the polymer which was precoated on the iron oxide nanoparticle surface. GIONs were then prepared by conjugating the azide-functionalized carbohydrate to the introduced alkynyl groups via click chemistry. Polyvinyl alcohol-coated and dextran-coated iron oxide NPs were chosen as scaffolds to attach two different carbohydrates, α-D-mannose and β-D-glucose, to fabricate multivalent GIONs, respectively. The multivalent GIONs demonstrated high binding affinities towards the corresponding lectins in both protein and cell chips. As a proof of concept, fluorescent GIONs (Gal-RhB-IONPs) were fabricated, which showed selective and efficient internalization by ASGP-R overexpressing HepG2 cells targeted.

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Attana biosensors provides a reliable, fast and versatile label-free method to study molecular interactions.

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