Attana biosensors provides a reliable, fast and versatile label-free method to study molecular interactions.
![Cellular analysis](https://www.accela.eu/files/fields/2/cellular-analysis-hex.jpg)
Automated microscopy and Spatial Proteomics
Real-time, label free cell analysis
Nano and micro particle analysis
![Flow cytometry](https://www.accela.eu/files/fields/3/flow-cytometry-hex.jpg)
Accelerate to discover
Related topics
Theranostics: From Mice to Men and Back
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Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
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Thursday, 11 July 2024, 16:00 CET | 10:00 EST
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Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics
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Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system
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High-frequency Ultrasound System For Preclinical Imaging
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Jun 1, 2016
A novel method for facile fabrication of glycopolymer-based iron oxide nanoparticles (GIONs) is developed. Via perfluorophenylazide photochemically induced C–H insertion, alkynyl groups were introduced onto the polymer which was precoated on the iron oxide nanoparticle surface. GIONs were then prepared by conjugating the azide-functionalized carbohydrate to the introduced alkynyl groups via click chemistry. Polyvinyl alcohol-coated and dextran-coated iron oxide NPs were chosen as scaffolds to attach two different carbohydrates, α-D-mannose and β-D-glucose, to fabricate multivalent GIONs, respectively. The multivalent GIONs demonstrated high binding affinities towards the corresponding lectins in both protein and cell chips. As a proof of concept, fluorescent GIONs (Gal-RhB-IONPs) were fabricated, which showed selective and efficient internalization by ASGP-R overexpressing HepG2 cells targeted.
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Attana biosensors provides a reliable, fast and versatile label-free method to study molecular interactions.
More info at:
www.attana.com/