A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.
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ACCELA educational webinar: Unlocking Spatial Biology with RareCyte Orion
Mar 16, 2023
Experience Spatial Biology with Orion Multiplex Imaging. Orion is a benchtop, high...
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Anesthesia settings and operation of Optical Imaging Systems: methods, animal handling, safety and regulatory...
NanoCellect Webinar: Optimizing the Cell Line Development Process with Microfluidic Cell Sorting
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Single-cell selection and cloning are required for bioengineering workflows such as antibody production, cell therapy,...
Webinar: Spatial Biology and immunofluorescence to study human pancreata in in type 1 diabete
Feb 9, 2023
In this webinar, Dr. Quesada-Masachs from La Jolla Institute for Immunology reveals the image analysis pipeline that...
Advances in Leukemia research using shear flow and Bioflux system
Feb 3, 2023
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...
Webinar: Dose Reduction and Image Enhancement in Preclinical Mouse Imaging using Deep Learning
Jan 31, 2023
In this webinar, ir. Florence Muller (Ghent University - University of Pennsylvania) is presenting two recent studies...
ACCELA Educational webinar series: Unlocking Spatial Biology with RareCyte Orion Technology
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Discover full slide, high-plex biomarker quantitation with the all-in-one spatial biology...
Practical aspects of an imaging study: live in vivo scanning
Nov 11, 2022
In this webinar, MOLECUBES will present a live in vivo demonstration, showing the entire workflow from animal...
Next generation karyotyping: detecting cancer-associated structural variants using optical maps
Apr 19, 2017
James Broach, PhD, Penn State Hershey, Pennsylvania, United States.
Identification of structural variants (SVs) is critical to the prognosis of acute myeloid leukemia (AML) and other hematologic malignancies. SVs are not readily identified by next generation sequencing methods and are currently diagnosed by cytogenetics, an intrinsically low resolution tool. Dr. James Broach from Penn State Hershey will discuss a new method for determining large SVs as a clinical tool for evaluating AML and other cancer genomes using Bionano optical mapping. Dr. Broach has applied this technology for detection of SVs in a variety of cancer cell lines and directly from leukemia patient blood samples. In all cases, they have identified all the SVs reported by classic cytogenetic analysis and, in addition, a large number of translocations, deletions and insertions not observed by cytogenetics.
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