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Responsive fluorescence probe for detection of Hypochlorous acid in live cells and animals

Spectral Instruments Imaging

Jan 17, 2019

In this work, a new fluorescence probe, PQI, was developed for monitoring of the HOCl level in biological samples. The...

Improved differentiation of Retinal Organoids stem cells derived using rotating-wall vessels

Synthecon

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Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a...

IncuCyte webinar recording: CAR T-cell therapy, frontiers in cancer Immunotherapy

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The success of immune checkpoint blockade adds new therapeutic category to Cancers are the most heterogenous group of...

CT‐analyzer plug‐ins: ROI shrink‐wrap and primitive ROI

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The ROI shrink‐wrap gives the possibility to automatically generate a region‐of‐interest by adapting to the shape of...

Jan 23, 2019

Cytek Aurora spectral flow cytometer - say hello to a new reality

Cytek Biosciences

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A prodigy that takes flow cytometry to the next level of performance and flexibility. With up to four lasers, three...

ACEA Biosciences launch xCELLigence RTCA software Pro for immunotherapy applications

Acea Biosciences

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RTCA Software Pro is an integrated software package for running and analyzing real time cell analysis data from...

Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

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Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...

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The need for ultra high field magnetic resonance imaging

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MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

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On the origin of replication by means of Bionano mapping

Jan 26, 2018

Life only exists because of the ability of cells to replicate, and death can come early when a cell’s replication spins out of control. Yet exactly where eukaryotic cells start when their large genomes need to be copied is still somewhat of a mystery. Studies looking into replication origins have largely focused on simple organisms with smaller genomes. Observing this process in large genomes like ours is difficult because eukaryotic cells have up to 50,000 replication start points per cell per cycle, and even the most commonly observed replication origin in the genome functions as such in just 10 percent of cells. To find answers to the question of where and when replication starts in individual cells, one needs a technology that can image and identify large single DNA molecules that are fluorescently labeled at high resolution and throughput… and of course we knew just what technology that could be!

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

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