Accelerate to discover

Back to filter

Related topics

Successful migration from radioactive irradiators to x-ray irradiators

Precision X-Ray

Dec 9, 2019

This paper summarizes about 9 years of effort by Mount Sinai to successfully migrate completely from radioactive...

New NovoCyte Advanteon - Performance you can trust with the flexibility you need

Acea Biosciences

Dec 6, 2019

The NovoCyte Advanteon flow cytometer builds upon the highly successful NovoCyte, and NovoCyte Quanteon, to provide an...

Webinar recording: 4D monitoring of bone and (re)modeling events using in vivo micro-CT

Bruker Biospin

Dec 4, 2019

Micro-CT is a powerful tool for the longitudinal monitoring of bones to acquire bone mass and architectural changes in...

Bioflux webinar: Flow dynamics influence on biofilm formation by Proteus mirabilis

Fluxion Biosciences

Dec 2, 2019

Catheter blockage by ureolytic biofilm-forming pathogens is a significant problem for health services, with 2,000...

Dec 10, 2019

Bruker MRI consistent quantification

Bruker Biospin

Nov 29, 2019

Regardless of the method, stability and reproducibility are a must for many laboratories. Identical protocols must...

Targeted sequencing of highly homologous genes using Cas9 digestion

Sage Science

Nov 25, 2019

Integrated DNA extraction, digestion, and size-selection using HLS-CATCH were introduced for addressing the problem of...

Multirad - Fully integrated x-ray irradiation system

Precision X-Ray

Nov 20, 2019

The new X-RAD 160 qube is suitable for either mounting on the lab bench or mobile on an optional wheeled cart, allowing...

Dec 10, 2019

AVATAR system: A unique capability for functional screening of tumor microenvironment

Xcell Biosciences

Nov 18, 2019

The AVATAR Cell Control System lets you generate your cells of interest and optimize to a growth rate, functional...

Show all topics (10)

On the origin of replication by means of Bionano mapping

Jan 26, 2018

Life only exists because of the ability of cells to replicate, and death can come early when a cell’s replication spins out of control. Yet exactly where eukaryotic cells start when their large genomes need to be copied is still somewhat of a mystery. Studies looking into replication origins have largely focused on simple organisms with smaller genomes. Observing this process in large genomes like ours is difficult because eukaryotic cells have up to 50,000 replication start points per cell per cycle, and even the most commonly observed replication origin in the genome functions as such in just 10 percent of cells. To find answers to the question of where and when replication starts in individual cells, one needs a technology that can image and identify large single DNA molecules that are fluorescently labeled at high resolution and throughput… and of course we knew just what technology that could be!

Read more

 

Scientific paper
Technical breakthrough
Application

Related technologies: Genome mapping

Get more info

Regina Fillerová

Field application specialist

Regina

Fillerová

+420 731 127 718

Send Message

Brand profile

BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

Related products

Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

show detail

Saphyr provides rapid, high-throughput, long-range genome mapping with unmatched structural variation discovery capabilities

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey