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Optical methylation mapping made simple

Apr 24, 2018

Yuval Ebenstein, professor in the department of chemical physics at Tel Aviv university and Bionano’s application scientists developed the new technology of DNA methylation labeling and imaging by a Bionano Irys system. As a result, we can now read the methylation status of the genome on long, single molecules while simultaneously mapping major structural variation on the same molecules. In the image above, you see a green signal repeat every 50 kbp – this is an unmethylated CpG island in a 50 kbp repeat.

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BioNano Genomics

A revolutionary NanoChannel technology for Genome mapping of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias.

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Genome maps of extremely long DNA without amplification, providing long-range contiguity and eliminating PCR bias

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