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"In our lab, we use microCT Skyscan 1276 for visualization of vasculature and cancer in mice model. Xtreme II is powerful tool for molecular imaging. In our research group, Xtreme II is commonly used to assess the biodistribution of novel drug candidates in small animal model."

Adam Novobilský, PhD

Dept. Pharmacology and Immunotherapy, Veterinary Research Institute, Brno, Czech Republic

In-Vivo Xtreme II - Bruker Biospin

Optical and X-ray small animal imaging system

Xtreme II, the most advanced preclinical Optical/X-ray imaging system, brings a new level of sensitivity, speed and versatility to preclinical imaging.

Discover important biological mechanisms in disease, treatments and monitoring using five imaging modalities including bioluminescence, multispectral VIS- NIR fluorescence, unique direct radioisotopic imaging and Cherenkov radiation.

 Key Applications:

  • Tumor and stem cell tracking
  • Luminescence imaging of inflammation
  • Optical imaging of PET probes with Cherenkov radiation
  • Tracking and validating single or multimodal nanoparticles
  • Imaging and validating new probes and biomarker
  • Non-invasively image changes in signaling cascades
  • Discover how genetics, small molecules and therapeutics affect biochemical pathways
  • Quantify changes in bone and soft tissue phenotype
  • High throughput pharmacodynamic studies

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https://www.bruker.com/products/preclinical-imaging/opticalx-ray-imaging/in-vivo-xtreme-new/overview.html
Miroslav Vecheta

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