"The Ami HTX optical imaging system is a flexible tool that we utilize for a range of in vivo and in vitro experiments. The software is intuitive and simple to use. This technology provides a great sensitivity, which is required for our experiments. The system is extremely stable, as there is no external refrigeration system to fail. The hardware is easy to operate and the compact size of the machine saves the working space." 

Dr Michal Šimíček

Medical Faculty, Ostrava,Czech Republic

Lago X is an exceptional tool for whole-body applications, with its exceptional reproducibility, signal stability and camera sensitivity, shortening imaging times to less then 1s. Based on our experience, we are able to detect metastases in cancer model much sooner and in more sites than other in-vivo systems. Lago X software is freely available for image processing and quantification, which allows involvement of broad research community into raw data analysis. Finally, we appreciate large field of view, which allows 10 adult mice to be imaged at once. Such features makes Lago X a breakthrough solution for high throughput and high demand in-vivo applications. 

Dr Jan Procházka

Biocev, Prague, Czech Republic

Ami HT / Ami HTX - Spectral Instruments Imaging

A new, high throughput benchmark for in-vivo imaging

Using Ami HT and Ami HTX (includes X-Ray imaging), researchers in pharma, academia, early stage biotech as well as global CROs can conduct optical imaging system for studying small animal disease model progression, response to therapy, and cell migration in-vivo.

The cutting edge patented LED based illumination provides unprecedented power and previously unattained sensitivity for FLI and BLI. The Ami HT and Ami HTX are also well suited when early detection and marking disease progression are of value.

The Ami HT and Ami HTX come equipped for the largest native FOV on the market based on comparable products from other vendors. Other products aspire to widen their FOV by using a corrective expansion lens, which by the laws of physics will reduce the sensitivity dramatically. Not the Ami HT which delivers a native FOV of 25cm x 17cm, easily imaging 5 mice at a time. In fact, the Ami HTX provides an outstanding 25cm x 15cm FOV for X-Ray as well. None of the other manufacturers have anything close to this powerful combination of sensitivity and multi-modal FOV.

The Ami HT is field upgradeable for X-Ray to the same spec as Ami HTX. Like the Lago, the Ami HT comes equipped with a solid state air-cooled camera and state of the art high performance imaging capabilities. Free, unlimited copies of AMIView software, coupled with competitive support plans, and low entry cost make the Ami HT and Ami HTX the sensible choice for many researchers. The instruments are absolutely calibrated.

Key features:

  • Bioluminescent imaging
  • Fluorescent imaging
  • X-Ray
  • High throughput
  • Pure LED illumination (patented)
  • 100X light intensity on specimen
  • 10 LED wavelengths from 430nm to 745nm
  • 10 filters included from 530nm to 790 nm
  • Selection of 20 filters available
  • Custom emission filters for plant imaging
  • Solid state cooled CCD camera (–90C), no leaks
  • High Performance Imager
  • CCD camera with back illumination
  • Ultra-wide category leading 25cm x 17cm optical FOV
  • X-Ray FOV is 25 x 15 cm
  • Up to 40kV maximum X-Ray energy
  • Field upgrade X-Ray
  • Field upgrade for Access Port
  • Field upgrade to high throughput configuration
  • Absolutely calibrated
  • Acquisition PC and monitor included
  • AMIView image analysis software – unlimited free copies
  • Vertical sliding door with reduced waste anesthesia gas
  • Rigid strong back high integrity structure

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A carboxymethyl dextran-based polymeric conjugate as the antigen carrier for cancer immunotherapy Squaraine fluorophore as a NIR-fluorescent probe for the in vivo detection of diagnostic enzymes Responsive fluorescence probe for detection of Hypochlorous acid in live cells and animals Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts Modified Beta-carotene-bound albumin nanoparticles for breast tumor ablation In Vivo Bioluminescence Imaging of Cobalt Accumulation in a Mouse Model Transcutaneous implantation of valproic acid-encapsulated Oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer at a single low dose Cancer cells resist mechanical destruction in the circulation via RhoA-myosin II axis Genotype-targeted local therapy of glioma Loss of Notch1 activity inhibits prostate cancer growth Insulin receptor substrate 1 is a substrate of the Pim protein kinases A mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection Elevated NSD3 histone methylation activity drives squamous cell lung cancer Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles High quality Bioluminescence and X-Ray analysis in lung squamous cell carcinoma Spectral Instruments Imaging webinar : The roles of preclinical optical imaging in cancer research Introducing New Aura 4.0 software The roles of preclinical optical imaging in cancer research Molecular imaging study design basics Quantitative 3D Optical Imaging for Lago AMI HTX installation in CEMEX Iasi, Romania Recorded webinar: Anesthesia Considerations in Small Animal Imaging Optimizing Gene Expression with Bioluminescence & the piggyBac System Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy Preclinical In Vivo Optical Imaging Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice Automatically Acquire Bioluminescent Kinetic Curve Data in Real Time Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics
Igor Valerián

Business director



+420 603 223 602

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